Application of a small molecule inhibitor screen approach to identify CXCR4 downstream signaling pat...
Application of a small molecule inhibitor screen approach to identify CXCR4 downstream signaling pathways that promote a mesenchymal and fulvestrant‑resistant phenotype in breast cancer cells
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Publisher
Greece: Spandidos Publications
Journal title
Language
English
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Publisher
Greece: Spandidos Publications
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Scope and Contents
Contents
Chemokine receptor 4 (CXCR4) and its ligand stromal-derived factor 1 (SDF-1) have well-characterized functions in cancer metastasis; however, the specific mechanisms through which CXCR4 promotes a metastatic and drug-resistant phenotype remain widely unknown. The aim of the present study was to demonstrate the application of a phenotypic screening...
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Full title
Application of a small molecule inhibitor screen approach to identify CXCR4 downstream signaling pathways that promote a mesenchymal and fulvestrant‑resistant phenotype in breast cancer cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7988660
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7988660
Other Identifiers
ISSN
1792-1074,0969-9538
E-ISSN
1792-1082
DOI
10.3892/ol.2021.12641
