Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid t...
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors
About this item
Full title
Author / Creator
Theruvath, Johanna , Sotillo, Elena , Mount, Christopher W. , Graef, Claus Moritz , Delaidelli, Alberto , Heitzeneder, Sabine , Labanieh, Louai , Dhingra, Shaurya , Leruste, Amaury , Majzner, Robbie G. , Xu, Peng , Mueller, Sabine , Yecies, Derek W. , Finetti, Martina A. , Williamson, Daniel , Johann, Pascal D. , Kool, Marcel , Pfister, Stefan , Hasselblatt, Martin , Frühwald, Michael C. , Delattre, Olivier , Surdez, Didier , Bourdeaut, Franck , Puget, Stephanie , Zaidi, Sakina , Mitra, Siddhartha S. , Cheshier, Samuel , Sorensen, Poul H. , Monje, Michelle and Mackall, Crystal L.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Atypical teratoid/rhabdoid tumors (ATRTs) typically arise in the central nervous system (CNS) of children under 3 years of age. Despite intensive multimodal therapy (surgery, chemotherapy and, if age permits, radiotherapy), median survival is 17 months
1
,
2
. We show that ATRTs robustly express
B7-H3
/
CD276
that does not r...
Alternative Titles
Full title
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors
Authors, Artists and Contributors
Author / Creator
Sotillo, Elena
Mount, Christopher W.
Graef, Claus Moritz
Delaidelli, Alberto
Heitzeneder, Sabine
Labanieh, Louai
Dhingra, Shaurya
Leruste, Amaury
Majzner, Robbie G.
Xu, Peng
Mueller, Sabine
Yecies, Derek W.
Finetti, Martina A.
Williamson, Daniel
Johann, Pascal D.
Kool, Marcel
Pfister, Stefan
Hasselblatt, Martin
Frühwald, Michael C.
Delattre, Olivier
Surdez, Didier
Bourdeaut, Franck
Puget, Stephanie
Zaidi, Sakina
Mitra, Siddhartha S.
Cheshier, Samuel
Sorensen, Poul H.
Monje, Michelle
Mackall, Crystal L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7992505
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7992505
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-020-0821-8
