Cyrius: accurate CYP2D6 genotyping using whole-genome sequencing data
Cyrius: accurate CYP2D6 genotyping using whole-genome sequencing data
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Responsible for the metabolism of ~21% of clinically used drugs,
CYP2D6
is a critical component of personalized medicine initiatives. Genotyping
CYP2D6
is challenging due to sequence similarity with its pseudogene paralog
CYP2D7
and a high number and variety of common structural variants (SVs). Here we describe a novel bioinformat...
Alternative Titles
Full title
Cyrius: accurate CYP2D6 genotyping using whole-genome sequencing data
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7997805
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7997805
Other Identifiers
ISSN
1470-269X
E-ISSN
1473-1150
DOI
10.1038/s41397-020-00205-5
