Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors
Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Systemic mastocytosis (SM) is a rare clonal hematologic neoplasm, driven, in almost all cases, by the activating KIT D816V mutation that leads to the growth and accumulation of neoplastic mast cells. While patients with advanced forms of SM have a poor prognosis, the introduction of KIT inhibitors (e.g., midostaurin, and avapritinib) has changed th...
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Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8001403
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8001403
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms22062983