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Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors

Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8001403

Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors

About this item

Full title

Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2021-03, Vol.22 (6), p.2983

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Systemic mastocytosis (SM) is a rare clonal hematologic neoplasm, driven, in almost all cases, by the activating KIT D816V mutation that leads to the growth and accumulation of neoplastic mast cells. While patients with advanced forms of SM have a poor prognosis, the introduction of KIT inhibitors (e.g., midostaurin, and avapritinib) has changed th...

Alternative Titles

Full title

Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8001403

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8001403

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms22062983

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