Determinism and contingencies shaped the evolution of mitochondrial protein import
Determinism and contingencies shaped the evolution of mitochondrial protein import
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Mitochondrial protein import requires outer membrane receptors that evolved independently in different lineages. Here we used quantitative proteomics and in vitro binding assays to investigate the substrate preferences of ATOM46 and ATOM69, the two mitochondrial import receptors of Trypanosoma brucei. The results show that ATOM46 prefers presequenc...
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Full title
Determinism and contingencies shaped the evolution of mitochondrial protein import
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8017667
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8017667
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2017774118