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pH and ROS sequentially responsive podophyllotoxin prodrug micelles with surface charge-switchable a...

pH and ROS sequentially responsive podophyllotoxin prodrug micelles with surface charge-switchable a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8023596

pH and ROS sequentially responsive podophyllotoxin prodrug micelles with surface charge-switchable and self-amplification drug release for combating multidrug resistance cancer

About this item

Full title

pH and ROS sequentially responsive podophyllotoxin prodrug micelles with surface charge-switchable and self-amplification drug release for combating multidrug resistance cancer

Publisher

England: Taylor & Francis

Journal title

Drug delivery, 2021-01, Vol.28 (1), p.680-691

Language

English

Formats

Publication information

Publisher

England: Taylor & Francis

More information

Scope and Contents

Contents

Multidrug resistance (MDR) is one of the main reasons for tumor chemotherapy failure. Podophyllotoxin (PPT) has been reported that can suppress MDR cancer cell growth; however, effective delivery of PPT to MDR cancer cells is challenged by cascaded bio-barriers. To effectively deliver PPT to MDR cancer cells, a PPT polymeric prodrug micelle (PCDMA)...

Alternative Titles

Full title

pH and ROS sequentially responsive podophyllotoxin prodrug micelles with surface charge-switchable and self-amplification drug release for combating multidrug resistance cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8023596

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8023596

Other Identifiers

ISSN

1071-7544

E-ISSN

1521-0464

DOI

10.1080/10717544.2021.1905750

How to access this item