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Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from s...

Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8027596

Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients

About this item

Full title

Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients

Publisher

England: Nature Publishing Group

Journal title

Neuropsychopharmacology (New York, N.Y.), 2021-02, Vol.46 (3), p.673-682

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

Human-induced pluripotent stem cells (hiPSCs) allow for the establishment of brain cellular models of psychiatric disorders that account for a patient’s genetic background. Here, we conducted an RNA-sequencing profiling study of hiPSC-derived cell lines from schizophrenia (SCZ) subjects, most of which are from a multiplex family, from the populatio...

Alternative Titles

Full title

Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8027596

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8027596

Other Identifiers

ISSN

0893-133X,1740-634X

E-ISSN

1740-634X

DOI

10.1038/s41386-020-00924-0

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