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The cGAS–STING pathway as a therapeutic target in inflammatory diseases

The cGAS–STING pathway as a therapeutic target in inflammatory diseases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8029610

The cGAS–STING pathway as a therapeutic target in inflammatory diseases

About this item

Full title

The cGAS–STING pathway as a therapeutic target in inflammatory diseases

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Immunology, 2021-09, Vol.21 (9), p.548-569

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The cGAS–STING signalling pathway has emerged as a key mediator of inflammation in the settings of infection, cellular stress and tissue damage. Underlying this broad involvement of the cGAS–STING pathway is its capacity to sense and regulate the cellular response towards microbial and host-derived DNAs, which serve as ubiquitous danger-associated...

Alternative Titles

Full title

The cGAS–STING pathway as a therapeutic target in inflammatory diseases

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8029610

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8029610

Other Identifiers

ISSN

1474-1733

E-ISSN

1474-1741

DOI

10.1038/s41577-021-00524-z

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