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Human Somatostatin SST4 Receptor Transgenic Mice: Construction and Brain Expression Pattern Characte...

Human Somatostatin SST4 Receptor Transgenic Mice: Construction and Brain Expression Pattern Characte...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8038480

Human Somatostatin SST4 Receptor Transgenic Mice: Construction and Brain Expression Pattern Characterization

About this item

Full title

Human Somatostatin SST4 Receptor Transgenic Mice: Construction and Brain Expression Pattern Characterization

Publisher

Basel: MDPI AG

Journal title

International journal of molecular sciences, 2021-04, Vol.22 (7), p.3758

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

Somatostatin receptor subtype 4 (SST4) has been shown to mediate analgesic, antidepressant and anti-inflammatory functions without endocrine actions; therefore, it is proposed to be a novel target for drug development. To overcome the species differences of SST4 receptor expression and function between humans and mice, we generated an SST4 humanize...

Alternative Titles

Full title

Human Somatostatin SST4 Receptor Transgenic Mice: Construction and Brain Expression Pattern Characterization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8038480

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8038480

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms22073758

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