c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate deh...
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
Journal title
Language
English
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Contents
NRF2, a redox sensitive transcription factor, is up-regulated in head and neck squamous cell carcinoma (HNSCC), however, the associated impact and regulatory mechanisms remain unclear.
The protein expression of NRF2 in HNSCC specimens was examined by IHC. The regulatory effect of c-MYC on NRF2 was validated by ChIP-qPCR, RT-qPCR and western blot...
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Full title
c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8039948
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8039948
Other Identifiers
ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.53417
