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NAD+ supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitopha...

NAD+ supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitopha...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8045911

NAD+ supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy

About this item

Full title

NAD+ supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy

Publisher

England: John Wiley & Sons, Inc

Journal title

Aging cell, 2021-04, Vol.20 (4), p.e13329-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Senescence phenotypes and mitochondrial dysfunction are implicated in aging and in premature aging diseases, including ataxia telangiectasia (A‐T). Loss of mitochondrial function can drive age‐related decline in the brain, but little is known about whether improving mitochondrial homeostasis alleviates senescence phenotypes. We demonstrate here tha...

Alternative Titles

Full title

NAD+ supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8045911

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8045911

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.13329

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