High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors
About this item
Full title
Author / Creator
Zhao, Yao , Du, Xiaoyu , Duan, Yinkai , Pan, Xiaoyan , Sun, Yifang , You, Tian , Han, Lin , Jin, Zhenming , Shang, Weijuan , Yu, Jing , Guo, Hangtian , Liu, Qianying , Wu, Yan , Peng, Chao , Wang, Jun , Zhu, Chenghao , Yang, Xiuna , Yang, Kailin , Lei, Ying , Guddat, Luke W. , Xu, Wenqing , Xiao, Gengfu , Sun, Lei , Zhang, Leike , Rao, Zihe and Yang, Haitao
Publisher
Beijing: Higher Education Press
Journal title
Language
English
Formats
Publication information
Publisher
Beijing: Higher Education Press
Subjects
More information
Scope and Contents
Contents
A new coronavirus (SARS-CoV-2) has been identified as the etiologic agent for the COVID-19 outbreak. Currently, effective treatment options remain very limited for this disease; therefore, there is an urgent need to identify new anti-COVID-19 agents. In this study, we screened over 6,000 compounds that included approved drugs, drug candidates in cl...
Alternative Titles
Full title
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors
Authors, Artists and Contributors
Author / Creator
Du, Xiaoyu
Duan, Yinkai
Pan, Xiaoyan
Sun, Yifang
You, Tian
Han, Lin
Jin, Zhenming
Shang, Weijuan
Yu, Jing
Guo, Hangtian
Liu, Qianying
Wu, Yan
Peng, Chao
Wang, Jun
Zhu, Chenghao
Yang, Xiuna
Yang, Kailin
Lei, Ying
Guddat, Luke W.
Xu, Wenqing
Xiao, Gengfu
Sun, Lei
Zhang, Leike
Rao, Zihe
Yang, Haitao
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8052528
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8052528
Other Identifiers
ISSN
1674-800X
E-ISSN
1674-8018
DOI
10.1007/s13238-021-00836-9
