Comparative analysis of assays to measure CAR T-cell-mediated cytotoxicity
Comparative analysis of assays to measure CAR T-cell-mediated cytotoxicity
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The antitumor efficacy of genetically engineered ‘living drugs’, including chimeric antigen receptor and T-cell receptor T cells, is influenced by their activation, proliferation, inhibition, and exhaustion. A sensitive and reproducible cytotoxicity assay that collectively reflects these functions is an essential requirement for translation of thes...
Alternative Titles
Full title
Comparative analysis of assays to measure CAR T-cell-mediated cytotoxicity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8064272
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8064272
Other Identifiers
ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/s41596-020-00467-0
