Population-based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene...
Population-based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high-grade serous ovarian cancer
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Author / Creator
Song, Honglin , Dicks, Ed M , Tyrer, Jonathan , Intermaggio, Maria , Chenevix-Trench, Georgia , Bowtell, David D , Traficante, Nadia , Group, AOCS , Brenton, James , Goranova, Teodora , Hosking, Karen , Piskorz, Anna , van Oudenhove, Elke , Doherty, Jen , Harris, Holly R , Rossing, Mary Anne , Duerst, Matthias , Dork, Thilo , Bogdanova, Natalia V , Modugno, Francesmary , Moysich, Kirsten , Odunsi, Kunle , Ness, Roberta , Karlan, Beth Y , Lester, Jenny , Jensen, Allan , Krüger Kjaer, Susanne , Høgdall, Estrid , Campbell, Ian G , Lázaro, Conxi , Pujara, Miguel Angel , Cunningham, Julie , Vierkant, Robert , Winham, Stacey J , Hildebrandt, Michelle , Huff, Chad , Li, Donghui , Wu, Xifeng , Yu, Yao , Permuth, Jennifer B , Levine, Douglas A , Schildkraut, Joellen M , Riggan, Marjorie J , Berchuck, Andrew , Webb, Penelope M , Group, OPAL Study , Cybulski, Cezary , Gronwald, Jacek , Jakubowska, Anna , Lubinski, Jan , Alsop, Jennifer , Harrington, Patricia , Chan, Isaac , Menon, Usha , Pearce, Celeste L , Wu, Anna H , de Fazio, Anna , Kennedy, Catherine J , Goode, Ellen , Ramus, Susan , Gayther, Simon and Pharoah, Paul
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
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Publisher
England: BMJ Publishing Group Ltd
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More information
Scope and Contents
Contents
PurposeThe known epithelial ovarian cancer (EOC) susceptibility genes account for less than 50% of the heritable risk of ovarian cancer suggesting that other susceptibility genes exist. The aim of this study was to evaluate the contribution to ovarian cancer susceptibility of rare deleterious germline variants in a set of candidate genes.MethodsWe...
Alternative Titles
Full title
Population-based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high-grade serous ovarian cancer
Authors, Artists and Contributors
Author / Creator
Dicks, Ed M
Tyrer, Jonathan
Intermaggio, Maria
Chenevix-Trench, Georgia
Bowtell, David D
Traficante, Nadia
Group, AOCS
Brenton, James
Goranova, Teodora
Hosking, Karen
Piskorz, Anna
van Oudenhove, Elke
Doherty, Jen
Harris, Holly R
Rossing, Mary Anne
Duerst, Matthias
Dork, Thilo
Bogdanova, Natalia V
Modugno, Francesmary
Moysich, Kirsten
Odunsi, Kunle
Ness, Roberta
Karlan, Beth Y
Lester, Jenny
Jensen, Allan
Krüger Kjaer, Susanne
Høgdall, Estrid
Campbell, Ian G
Lázaro, Conxi
Pujara, Miguel Angel
Cunningham, Julie
Vierkant, Robert
Winham, Stacey J
Hildebrandt, Michelle
Huff, Chad
Li, Donghui
Wu, Xifeng
Yu, Yao
Permuth, Jennifer B
Levine, Douglas A
Schildkraut, Joellen M
Riggan, Marjorie J
Berchuck, Andrew
Webb, Penelope M
Group, OPAL Study
Cybulski, Cezary
Gronwald, Jacek
Jakubowska, Anna
Lubinski, Jan
Alsop, Jennifer
Harrington, Patricia
Chan, Isaac
Menon, Usha
Pearce, Celeste L
Wu, Anna H
de Fazio, Anna
Kennedy, Catherine J
Goode, Ellen
Ramus, Susan
Gayther, Simon
Pharoah, Paul
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8086250
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8086250
Other Identifiers
ISSN
0022-2593,1468-6244
E-ISSN
1468-6244
DOI
10.1136/jmedgenet-2019-106739
