Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10
Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10
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Publisher
United States: American Society for Cell Biology
Journal title
Language
English
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Publisher
United States: American Society for Cell Biology
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Scope and Contents
Contents
Insulin signaling mobilizes glucose transporter 4 (GLUT4) from the trans-Golgi network (TGN) through the AKT-TBC1D4-RAB10 signaling module. GLUT4 localizes to a region of the TGN responsible for retention and release of ATP7A copper transporter and the sorting of lysosomal enzymes to late endosomes.
Insulin controls glucose uptake into muscle an...
Alternative Titles
Full title
Insulin-promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8098823
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8098823
Other Identifiers
ISSN
1059-1524
E-ISSN
1939-4586
DOI
10.1091/mbc.E20-06-0356
