Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibr...
Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibrosis in the nonhuman primate
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Publisher
United States: Society for the Study of Reproduction
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Language
English
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United States: Society for the Study of Reproduction
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Contents
Oocytes are highly radiosensitive, so agents that prevent radiation-induced ovarian follicle destruction are important fertility preservation strategies. A previous study in rhesus macaques demonstrated that ovarian treatment with antiapoptotic agents, sphingosine-1-phosphate (S1P) and FTY720, its long-acting mimetic, preserved follicles following...
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Full title
Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibrosis in the nonhuman primate
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8111238
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8111238
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ISSN
0006-3363
E-ISSN
1529-7268
DOI
10.1093/biolre/ioab012