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Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibr...

Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8111238

Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibrosis in the nonhuman primate

About this item

Full title

Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibrosis in the nonhuman primate

Publisher

United States: Society for the Study of Reproduction

Journal title

Biology of reproduction, 2021-05, Vol.104 (5), p.1058-1070

Language

English

Formats

Publication information

Publisher

United States: Society for the Study of Reproduction

More information

Scope and Contents

Contents

Oocytes are highly radiosensitive, so agents that prevent radiation-induced ovarian follicle destruction are important fertility preservation strategies. A previous study in rhesus macaques demonstrated that ovarian treatment with antiapoptotic agents, sphingosine-1-phosphate (S1P) and FTY720, its long-acting mimetic, preserved follicles following...

Alternative Titles

Full title

Sphingosine-1-phosphate and its mimetic FTY720 do not protect against radiation-induced ovarian fibrosis in the nonhuman primate

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8111238

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8111238

Other Identifiers

ISSN

0006-3363

E-ISSN

1529-7268

DOI

10.1093/biolre/ioab012

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