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Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling

Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8120213

Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling

About this item

Full title

Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling

Publisher

Australia: Ivyspring International Publisher Pty Ltd

Journal title

Theranostics, 2021-01, Vol.11 (13), p.6491-6506

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

TGFβ signaling pathway controls tissue fibrotic remodeling, a hallmark in many diseases leading to organ injury and failure. In this study, we address the role of Apilimod, a pharmacological inhibitor of the lipid kinase PIKfyve, in the regulation of cardiac pathological fibrotic remodeling and TGFβ signaling pathway.
The effects of Apilimod tre...

Alternative Titles

Full title

Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8120213

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8120213

Other Identifiers

ISSN

1838-7640

E-ISSN

1838-7640

DOI

10.7150/thno.55821

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