Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling
Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
Journal title
Language
English
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Scope and Contents
Contents
TGFβ signaling pathway controls tissue fibrotic remodeling, a hallmark in many diseases leading to organ injury and failure. In this study, we address the role of Apilimod, a pharmacological inhibitor of the lipid kinase PIKfyve, in the regulation of cardiac pathological fibrotic remodeling and TGFβ signaling pathway.
The effects of Apilimod tre...
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Full title
Apilimod alters TGFβ signaling pathway and prevents cardiac fibrotic remodeling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8120213
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8120213
Other Identifiers
ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.55821