Single-cell multi-omics analysis of the immune response in COVID-19
Single-cell multi-omics analysis of the immune response in COVID-19
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Author / Creator
Stephenson, Emily , Reynolds, Gary , Botting, Rachel A. , Calero-Nieto, Fernando J. , Morgan, Michael D. , Tuong, Zewen Kelvin , Bach, Karsten , Sungnak, Waradon , Worlock, Kaylee B. , Yoshida, Masahiro , Kumasaka, Natsuhiko , Kania, Katarzyna , Engelbert, Justin , Olabi, Bayanne , Spegarova, Jarmila Stremenova , Wilson, Nicola K. , Mende, Nicole , Jardine, Laura , Gardner, Louis C. S. , Goh, Issac , Horsfall, Dave , McGrath, Jim , Webb, Simone , Mather, Michael W. , Lindeboom, Rik G. H. , Dann, Emma , Huang, Ni , Polanski, Krzysztof , Prigmore, Elena , Gothe, Florian , Scott, Jonathan , Payne, Rebecca P. , Baker, Kenneth F. , Hanrath, Aidan T. , Schim van der Loeff, Ina C. D. , Barr, Andrew S. , Sanchez-Gonzalez, Amada , Bergamaschi, Laura , Mescia, Federica , Barnes, Josephine L. , Kilich, Eliz , de Wilton, Angus , Saigal, Anita , Saleh, Aarash , Janes, Sam M. , Smith, Claire M. , Gopee, Nusayhah , Wilson, Caroline , Coupland, Paul , Coxhead, Jonathan M. , Kiselev, Vladimir Yu , van Dongen, Stijn , Bacardit, Jaume , King, Hamish W. , Rostron, Anthony J. , Simpson, A. John , Hambleton, Sophie , Laurenti, Elisa , Lyons, Paul A. , Meyer, Kerstin B. , Nikolić, Marko Z. , Duncan, Christopher J. A. , Smith, Kenneth G. C. , Teichmann, Sarah A. , Clatworthy, Menna R. , Marioni, John C. , Göttgens, Berthold , Haniffa, Muzlifah and Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID-19 BioResource Collaboration
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Analysis of human blood immune cells provides insights into the coordinated response to viral infections such as severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019 (COVID-19). We performed single-cell transcriptome, surface proteome and T and B lymphocyte antigen receptor analyses of over 780,000 peripheral blood...
Alternative Titles
Full title
Single-cell multi-omics analysis of the immune response in COVID-19
Authors, Artists and Contributors
Author / Creator
Reynolds, Gary
Botting, Rachel A.
Calero-Nieto, Fernando J.
Morgan, Michael D.
Tuong, Zewen Kelvin
Bach, Karsten
Sungnak, Waradon
Worlock, Kaylee B.
Yoshida, Masahiro
Kumasaka, Natsuhiko
Kania, Katarzyna
Engelbert, Justin
Olabi, Bayanne
Spegarova, Jarmila Stremenova
Wilson, Nicola K.
Mende, Nicole
Jardine, Laura
Gardner, Louis C. S.
Goh, Issac
Horsfall, Dave
McGrath, Jim
Webb, Simone
Mather, Michael W.
Lindeboom, Rik G. H.
Dann, Emma
Huang, Ni
Polanski, Krzysztof
Prigmore, Elena
Gothe, Florian
Scott, Jonathan
Payne, Rebecca P.
Baker, Kenneth F.
Hanrath, Aidan T.
Schim van der Loeff, Ina C. D.
Barr, Andrew S.
Sanchez-Gonzalez, Amada
Bergamaschi, Laura
Mescia, Federica
Barnes, Josephine L.
Kilich, Eliz
de Wilton, Angus
Saigal, Anita
Saleh, Aarash
Janes, Sam M.
Smith, Claire M.
Gopee, Nusayhah
Wilson, Caroline
Coupland, Paul
Coxhead, Jonathan M.
Kiselev, Vladimir Yu
van Dongen, Stijn
Bacardit, Jaume
King, Hamish W.
Rostron, Anthony J.
Simpson, A. John
Hambleton, Sophie
Laurenti, Elisa
Lyons, Paul A.
Meyer, Kerstin B.
Nikolić, Marko Z.
Duncan, Christopher J. A.
Smith, Kenneth G. C.
Teichmann, Sarah A.
Clatworthy, Menna R.
Marioni, John C.
Göttgens, Berthold
Haniffa, Muzlifah
Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID-19 BioResource Collaboration
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8121667
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8121667
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/s41591-021-01329-2
