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LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy

LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8122078

LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy

About this item

Full title

LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2021-05, Vol.23 (5), p.526-537

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Major histocompatibility complex-I (MHC-I) presents tumour antigens to CD8
+
T cells and triggers anti-tumour immunity. Humans may have 30,000–60,000 long noncoding RNAs (lncRNAs). However, it remains poorly understood whether lncRNAs affect tumour immunity. Here, we identify a lncRNA, lncRNA inducing MHC-I and immunogenicity of tumour (LIMIT...

Alternative Titles

Full title

LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8122078

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8122078

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-021-00672-3

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