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Lumican Inhibits Osteoclastogenesis and Bone Resorption by Suppressing Akt Activity

Lumican Inhibits Osteoclastogenesis and Bone Resorption by Suppressing Akt Activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8124849

Lumican Inhibits Osteoclastogenesis and Bone Resorption by Suppressing Akt Activity

About this item

Full title

Lumican Inhibits Osteoclastogenesis and Bone Resorption by Suppressing Akt Activity

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2021-04, Vol.22 (9), p.4717

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Lumican, a ubiquitously expressed small leucine-rich proteoglycan, has been utilized in diverse biological functions. Recent experiments demonstrated that lumican stimulates preosteoblast viability and differentiation, leading to bone formation. To further understand the role of lumican in bone metabolism, we investigated its effects on osteoclast...

Alternative Titles

Full title

Lumican Inhibits Osteoclastogenesis and Bone Resorption by Suppressing Akt Activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8124849

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8124849

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms22094717

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