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Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblast...

Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblast...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8159701

Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts

About this item

Full title

Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2021-06, Vol.131 (11)

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Cancer-associated fibroblasts (CAF) may exert tumor-promoting and tumor-suppressive functions, but the mechanisms underlying these opposing effects remain elusive. Here, we sought to understand these potentially opposing functions by interrogating functional relationships among CAF subtypes, their mediators, desmoplasia, and tumor growth in a wide...

Alternative Titles

Full title

Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8159701

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8159701

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI146987

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