Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease
About this item
Full title
Author / Creator
Bao, Wen-Dai , Pang, Pei , Zhou, Xiao-Ting , Hu, Fan , Xiong, Wan , Chen, Kai , Wang, Jing , Wang, Fudi , Xie, Dong , Hu, Ya-Zhuo , Han, Zhi-Tao , Zhang, Hong-Hong , Wang, Wang-Xia , Nelson, Peter T. , Chen, Jian-Guo , Lu, Youming , Man, Heng-Ye , Liu, Dan and Zhu, Ling-Qiang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Iron homeostasis disturbance has been implicated in Alzheimer’s disease (AD), and excess iron exacerbates oxidative damage and cognitive defects. Ferroptosis is a nonapoptotic form of cell death dependent upon intracellular iron. However, the involvement of ferroptosis in the pathogenesis of AD remains elusive. Here, we report that ferroportin1 (Fp...
Alternative Titles
Full title
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8166828
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8166828
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-020-00685-9
