Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in...
Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line
About this item
Full title
Author / Creator
Seo, Hidetaka , Masuda, Hitomi , Asagoshi, Kenjiro , Uchiki, Tomoaki , Kawata, Shigehisa , Sasaki, Goh , Yabuki, Takashi , Miyai, Shunsuke , Takahashi, Naoki , Hashimoto, Shu-ichi , Sawada, Atsushi , Takaiwa, Aki , Koyama, Chika , Tamai, Kanako , Kurosawa, Kohei , Lin, Ke-Yi , Ohta, Kunihiro and Nakazaki, Yukoh
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Monoclonal antibodies (mAbs) are widely utilized as therapeutic drugs for various diseases, such as cancer, autoimmune diseases, and infectious diseases. Using the avian-derived B cell line DT40, we previously developed an antibody display technology, namely, the ADLib system, which rapidly generates antigen-specific mAbs. Here, we report the devel...
Alternative Titles
Full title
Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8166883
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8166883
Other Identifiers
ISSN
1672-7681
E-ISSN
2042-0226
DOI
10.1038/s41423-020-0440-9
