Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL
Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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In chronic lymphocytic leukemia (CLL), the lymph node (LN) microenvironment delivers critical survival signals by inducing the expression of anti-apoptotic Bcl-2 members Bcl-XL, Bfl-1, and Mcl-1, resulting in apoptosis blockade. We determined previously that resistance against various drugs, among which is the clinically applied BH3 mimetic venetoc...
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Full title
Regulation of Bcl-XL by non-canonical NF-κB in the context of CD40-induced drug resistance in CLL
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8167103
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8167103
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-020-00692-w
