Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition
About this item
Full title
Author / Creator
Inoue, Daichi , Polaski, Jacob T. , Taylor, Justin , Castel, Pau , Chen, Sisi , Kobayashi, Susumu , Hogg, Simon J. , Hayashi, Yasutaka , Pineda, Jose Mario Bello , El Marabti, Ettaib , Erickson, Caroline , Knorr, Katherine , Fukumoto, Miki , Yamazaki, Hiromi , Tanaka, Atsushi , Fukui, Chie , Lu, Sydney X. , Durham, Benjamin H. , Liu, Bo , Wang, Eric , Mehta, Sanjoy , Zakheim, Daniel , Garippa, Ralph , Penson, Alex , Chew, Guo-Liang , McCormick, Frank , Bradley, Robert K. and Abdel-Wahab, Omar
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Most eukaryotes harbor two distinct pre-mRNA splicing machineries: the major spliceosome, which removes >99% of introns, and the minor spliceosome, which removes rare, evolutionarily conserved introns. Although hypothesized to serve important regulatory functions, physiologic roles of the minor spliceosome are not well understood. For example, the...
Alternative Titles
Full title
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition
Authors, Artists and Contributors
Author / Creator
Polaski, Jacob T.
Taylor, Justin
Castel, Pau
Chen, Sisi
Kobayashi, Susumu
Hogg, Simon J.
Hayashi, Yasutaka
Pineda, Jose Mario Bello
El Marabti, Ettaib
Erickson, Caroline
Knorr, Katherine
Fukumoto, Miki
Yamazaki, Hiromi
Tanaka, Atsushi
Fukui, Chie
Lu, Sydney X.
Durham, Benjamin H.
Liu, Bo
Wang, Eric
Mehta, Sanjoy
Zakheim, Daniel
Garippa, Ralph
Penson, Alex
Chew, Guo-Liang
McCormick, Frank
Bradley, Robert K.
Abdel-Wahab, Omar
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8177065
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8177065
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-021-00828-9
