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Hepatitis C virus modulates signal peptide peptidase to alter host protein processing

Hepatitis C virus modulates signal peptide peptidase to alter host protein processing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8179148

Hepatitis C virus modulates signal peptide peptidase to alter host protein processing

About this item

Full title

Hepatitis C virus modulates signal peptide peptidase to alter host protein processing

Publisher

Washington: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (22), p.1-12

Language

English

Formats

Publication information

Publisher

Washington: National Academy of Sciences

More information

Scope and Contents

Contents

Immunoevasins are viral proteins that prevent antigen presentation on major histocompatibility complex (MHC) class I, thus evading host immune recognition. Hepatitis C virus (HCV) evades immune surveillance to induce chronic infection; however, how HCV-infected hepatocytes affect immune cells and evade immune recognition remains unclear. Herein, we...

Alternative Titles

Full title

Hepatitis C virus modulates signal peptide peptidase to alter host protein processing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8179148

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8179148

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2026184118

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