Sequential ubiquitination of p53 by TRIM28, RLIM, and MDM2 in lung tumorigenesis
Sequential ubiquitination of p53 by TRIM28, RLIM, and MDM2 in lung tumorigenesis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Tripartite motif-containing 28 (TRIM28) is an E3 ubiquitin ligase harboring multiple cellular functions. We found that the TRIM28 protein is frequently overexpressed in patients with lung cancer. The stable overexpression of TRIM28 in lung cancer cells and xenograft models significantly increased the proliferation, migration, and invasiveness, wher...
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Sequential ubiquitination of p53 by TRIM28, RLIM, and MDM2 in lung tumorigenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8184939
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8184939
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ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/s41418-020-00701-y
