Leptin receptor expression in the dorsomedial hypothalamus stimulates breathing during NREM sleep in...
Leptin receptor expression in the dorsomedial hypothalamus stimulates breathing during NREM sleep in db/db mice
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Author / Creator
Pho, Huy , Berger, Slava , Freire, Carla , Kim, Lenise J , Shin, Mi-Kyung , Streeter, Stone R , Hosamane, Nishitha , Cabassa, Meaghan E , Anokye-Danso, Frederick , Dergacheva, Olga , Amorim, Mateus R , Fleury-Curado, Thomaz , Jun, Jonathan C , Schwartz, Alan R , Ahima, Rexford S , Mendelowitz, David and Polotsky, Vsevolod Y
Publisher
US: Oxford University Press
Journal title
Language
English
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Publisher
US: Oxford University Press
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Contents
Abstract
Study Objectives
Obesity leads to obstructive sleep apnea (OSA), which is recurrent upper airway obstruction during sleep, and obesity hypoventilation syndrome (OHS), hypoventilation during sleep resulting in daytime hypercapnia. Impaired leptin signaling in the brain was implicated in both conditions, but mechanisms are unknown. We...
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Full title
Leptin receptor expression in the dorsomedial hypothalamus stimulates breathing during NREM sleep in db/db mice
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Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8193564
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8193564
Other Identifiers
ISSN
0161-8105
E-ISSN
1550-9109
DOI
10.1093/sleep/zsab046
