The Role of HPA Axis and Allopregnanolone on the Neurobiology of Major Depressive Disorders and PTSD
The Role of HPA Axis and Allopregnanolone on the Neurobiology of Major Depressive Disorders and PTSD
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MDPI
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Language
English
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MDPI
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Contents
Under stressful conditions, the hypothalamic-pituitary-adrenal (HPA) axis acts to promote transitory physiological adaptations that are often resolved after the stressful stimulus is no longer present. In addition to corticosteroids (e.g., cortisol), the neurosteroid allopregnanolone (3α,5α-tetrahydroprogesterone, 3α-hydroxy-5α-pregnan-20-one) part...
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Full title
The Role of HPA Axis and Allopregnanolone on the Neurobiology of Major Depressive Disorders and PTSD
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8197074
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8197074
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ISSN
1422-0067
E-ISSN
1422-0067
DOI
10.3390/ijms22115495
