Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys
Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys
About this item
Full title
Author / Creator
Tao, Yunlong , Vermilyea, Scott C. , Zammit, Matthew , Lu, Jianfeng , Olsen, Miles , Metzger, Jeanette M. , Yao, Lin , Chen, Yuejun , Phillips, Sean , Holden, James E. , Bondarenko, Viktoriya , Block, Walter F. , Barnhart, Todd E. , Schultz-Darken, Nancy , Brunner, Kevin , Simmons, Heather , Christian, Bradley T. , Emborg, Marina E. and Zhang, Su-Chun
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Degeneration of dopamine (DA) neurons in the midbrain underlies the pathogenesis of Parkinson’s disease (PD). Supplement of DA via L-DOPA alleviates motor symptoms but does not prevent the progressive loss of DA neurons. A large body of experimental studies, including those in nonhuman primates, demonstrates that transplantation of fetal mesencepha...
Alternative Titles
Full title
Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys
Authors, Artists and Contributors
Author / Creator
Vermilyea, Scott C.
Zammit, Matthew
Lu, Jianfeng
Olsen, Miles
Metzger, Jeanette M.
Yao, Lin
Chen, Yuejun
Phillips, Sean
Holden, James E.
Bondarenko, Viktoriya
Block, Walter F.
Barnhart, Todd E.
Schultz-Darken, Nancy
Brunner, Kevin
Simmons, Heather
Christian, Bradley T.
Emborg, Marina E.
Zhang, Su-Chun
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8198752
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8198752
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-021-01257-1
