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Protein Aggregation Landscape in Neurodegenerative Diseases: Clinical Relevance and Future Applicati...

Protein Aggregation Landscape in Neurodegenerative Diseases: Clinical Relevance and Future Applicati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8199687

Protein Aggregation Landscape in Neurodegenerative Diseases: Clinical Relevance and Future Applications

About this item

Full title

Protein Aggregation Landscape in Neurodegenerative Diseases: Clinical Relevance and Future Applications

Publisher

MDPI

Journal title

International journal of molecular sciences, 2021-06, Vol.22 (11), p.6016

Language

English

Formats

Publication information

Publisher

MDPI

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Intrinsic disorder is a natural feature of polypeptide chains, resulting in the lack of a defined three-dimensional structure. Conformational changes in intrinsically disordered regions of a protein lead to unstable β-sheet enriched intermediates, which are stabilized by intermolecular interactions with other β-sheet enriched molecules, producing s...

Alternative Titles

Full title

Protein Aggregation Landscape in Neurodegenerative Diseases: Clinical Relevance and Future Applications

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8199687

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8199687

Other Identifiers

ISSN

1422-0067

E-ISSN

1422-0067

DOI

10.3390/ijms22116016

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