Critical role of the CD44lowCD62Llow CD8⁺ T cell subset in restoring antitumor immunity in aged mice
Critical role of the CD44lowCD62Llow CD8⁺ T cell subset in restoring antitumor immunity in aged mice
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Publisher
Washington: National Academy of Sciences
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Language
English
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Publisher
Washington: National Academy of Sciences
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Contents
CD8⁺ T cells play a central role in antitumor immune responses that kill cancer cells directly. In aged individuals, CD8⁺ T cell immunity is strongly suppressed, which is associated with cancer and other agerelated diseases. The mechanism underlying this age-related decrease in immune function remains largely unknown. This study investigated the ro...
Alternative Titles
Full title
Critical role of the CD44lowCD62Llow CD8⁺ T cell subset in restoring antitumor immunity in aged mice
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8201912
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8201912
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/PNAS.2103730118
