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The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι

The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8201919

The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι

About this item

Full title

The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2021-06, Vol.118 (23), p.1-12

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic and has claimed over 2 million lives worldwide. Although the genetic sequences of SARS-CoV and SARS-CoV-2 have high homology, the clinical and pathological characteristics of COVID-19 differ significantly from those of SARS. How and whethe...

Alternative Titles

Full title

The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8201919

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8201919

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2024202118

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