Development of a physiologically relevant and easily scalable LUHMES cell-based model of G2019S LRRK...
Development of a physiologically relevant and easily scalable LUHMES cell-based model of G2019S LRRK2-driven Parkinson's disease
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Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
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Publisher
England: The Company of Biologists Ltd
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Scope and Contents
Contents
Parkinson's disease (PD) is a fatal neurodegenerative disorder that is primarily caused by the degeneration and loss of dopaminergic neurons of the substantia nigra in the ventral midbrain. Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of late-onset PD identified to date, with G2019S being the most frequent LRR...
Alternative Titles
Full title
Development of a physiologically relevant and easily scalable LUHMES cell-based model of G2019S LRRK2-driven Parkinson's disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8214734
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8214734
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.048017
