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An optimal antitumor response by a novel CEA/CD3 bispecific antibody for colorectal cancers

An optimal antitumor response by a novel CEA/CD3 bispecific antibody for colorectal cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8220303

An optimal antitumor response by a novel CEA/CD3 bispecific antibody for colorectal cancers

About this item

Full title

An optimal antitumor response by a novel CEA/CD3 bispecific antibody for colorectal cancers

Publisher

United States: Oxford University Press

Journal title

Antibody Therapeutics, 2021-04, Vol.4 (2), p.90-100

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

Abstract
Background
CD3-based bispecific T cell engagers (bsTCEs) are one of the most promising bispecific antibodies for effective cancer treatments. To elicit target-specific T cell-mediated cytotoxicity, these bsTCEs contain at least one binding unit directed against a tumor antigen and another binding unit targeting CD3 in T cell receptor...

Alternative Titles

Full title

An optimal antitumor response by a novel CEA/CD3 bispecific antibody for colorectal cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8220303

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8220303

Other Identifiers

ISSN

2516-4236

E-ISSN

2516-4236

DOI

10.1093/abt/tbab009

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