New insights into the catalytic mechanism of the SARS-CoV-2 main protease: an ONIOM QM/MM approach
New insights into the catalytic mechanism of the SARS-CoV-2 main protease: an ONIOM QM/MM approach
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Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publication information
Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
SARS-CoV-2 M
pro
, also known as the main protease or 3C-like protease, is a key enzyme involved in the replication process of the virus that is causing the COVID-19 pandemic. It is also the most promising antiviral drug target targeting SARS-CoV-2 virus. In this work, the catalytic mechanism of M
pro
was studied using the full model of...
Alternative Titles
Full title
New insights into the catalytic mechanism of the SARS-CoV-2 main protease: an ONIOM QM/MM approach
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8224256
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8224256
Other Identifiers
ISSN
1381-1991
E-ISSN
1573-501X
DOI
10.1007/s11030-021-10259-7
