Serum IGF1 and linear growth in children with congenital leptin deficiency before and after leptin s...
Serum IGF1 and linear growth in children with congenital leptin deficiency before and after leptin substitution
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Background
Evidence from in vitro and rodent studies suggests that leptin, a key signal of long-term energy reserves, promotes IGF1 synthesis and linear growth. This effect of leptin has not been fully investigated in humans. The aim of our study was to investigate the effect of leptin substitution on growth factors and linear growth in children...
Alternative Titles
Full title
Serum IGF1 and linear growth in children with congenital leptin deficiency before and after leptin substitution
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8236407
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8236407
Other Identifiers
ISSN
0307-0565
E-ISSN
1476-5497
DOI
10.1038/s41366-021-00809-2
