The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D
The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D
About this item
Full title
Author / Creator
Chaikovsky, Andrea C. , Li, Chuan , Jeng, Edwin E. , Loebell, Samuel , Lee, Myung Chang , Murray, Christopher W. , Cheng, Ran , Demeter, Janos , Swaney, Danielle L. , Chen, Si-Han , Newton, Billy W. , Johnson, Jeffrey R. , Drainas, Alexandros P. , Shue, Yan Ting , Seoane, Jose A. , Srinivasan, Preethi , He, Andy , Yoshida, Akihiro , Hipkins, Susan Q. , McCrea, Edel , Poltorack, Carson D. , Krogan, Nevan J. , Diehl, J. Alan , Kong, Christina , Jackson, Peter K. , Curtis, Christina , Petrov, Dmitri A. , Bassik, Michael C. , Winslow, Monte M. and Sage, Julien
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The initiation of cell division integrates a large number of intra- and extracellular inputs. D-type cyclins (hereafter, cyclin D) couple these inputs to the initiation of DNA replication
1
. Increased levels of cyclin D promote cell division by activating cyclin-dependent kinases 4 and 6 (hereafter, CDK4/6), which in turn phosphorylate and i...
Alternative Titles
Full title
The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D
Authors, Artists and Contributors
Author / Creator
Li, Chuan
Jeng, Edwin E.
Loebell, Samuel
Lee, Myung Chang
Murray, Christopher W.
Cheng, Ran
Demeter, Janos
Swaney, Danielle L.
Chen, Si-Han
Newton, Billy W.
Johnson, Jeffrey R.
Drainas, Alexandros P.
Shue, Yan Ting
Seoane, Jose A.
Srinivasan, Preethi
He, Andy
Yoshida, Akihiro
Hipkins, Susan Q.
McCrea, Edel
Poltorack, Carson D.
Krogan, Nevan J.
Diehl, J. Alan
Kong, Christina
Jackson, Peter K.
Curtis, Christina
Petrov, Dmitri A.
Bassik, Michael C.
Winslow, Monte M.
Sage, Julien
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8246597
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8246597
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03474-7
