The blood–brain barrier and blood–tumour barrier in brain tumours and metastases
The blood–brain barrier and blood–tumour barrier in brain tumours and metastases
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Scope and Contents
Contents
For a blood-borne cancer therapeutic agent to be effective, it must cross the blood vessel wall to reach cancer cells in adequate quantities, and it must overcome the resistance conferred by the local microenvironment around cancer cells. The brain microenvironment can thwart the effectiveness of drugs against primary brain tumours as well as brain...
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Full title
The blood–brain barrier and blood–tumour barrier in brain tumours and metastases
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8246629
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8246629
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/s41568-019-0205-x