HIF-1α is a negative regulator of interferon regulatory factors: Implications for interferon product...
HIF-1α is a negative regulator of interferon regulatory factors: Implications for interferon production by hypoxic monocytes
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Patients with severe COVID-19 infection exhibit a low level of oxygen in affected tissue and blood. To understand the pathophysiology of COVID-19 infection, it is therefore necessary to understand cell function during hypoxia. We investigated aspects of human monocyte activation under hypoxic conditions. HMGB1 is an alarmin released by stressed cel...
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Full title
HIF-1α is a negative regulator of interferon regulatory factors: Implications for interferon production by hypoxic monocytes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8256008
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8256008
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.2106017118