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Origin of complexity in haemoglobin evolution

Origin of complexity in haemoglobin evolution

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8259614

Origin of complexity in haemoglobin evolution

About this item

Full title

Origin of complexity in haemoglobin evolution

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2020-05, Vol.581 (7809), p.480-485

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Most proteins associate into multimeric complexes with specific architectures
1
,
2
, which often have functional properties such as cooperative ligand binding or allosteric regulation
3
. No detailed knowledge is available about how any multimer and its functions arose during evolution. Here we use ancestral protein reconstructio...

Alternative Titles

Full title

Origin of complexity in haemoglobin evolution

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8259614

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8259614

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-020-2292-y

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