Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-spe...
Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons
About this item
Full title
Author / Creator
Wang, Liheng , Liu, Yang , Stratigopoulos, George , Panigrahi, Sunil , Sui, Lina , Zhang, Yiying , Leduc, Charles A. , Glover, Hannah J. , De Rosa, Maria Caterina , Burnett, Lisa C. , Williams, Damian J. , Shang, Linshan , Goland, Robin , Tsang, Stephen H. , Wardlaw, Sharon , Egli, Dieter , Zheng, Deyou , Doege, Claudia A. and Leibel, Rudolph L.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Bardet-Biedl syndrome (BBS) is a rare autosomal recessive disorder caused by mutations in genes encoding components of the primary cilium and is characterized by hyperphagic obesity. To investigate the molecular basis of obesity in human BBS, we developed a cellular model of BBS using induced pluripotent stem cell-derived (iPSC-derived) hypothalami...
Alternative Titles
Full title
Bardet-Biedl syndrome proteins regulate intracellular signaling and neuronal function in patient-specific iPSC-derived neurons
Authors, Artists and Contributors
Author / Creator
Liu, Yang
Stratigopoulos, George
Panigrahi, Sunil
Sui, Lina
Zhang, Yiying
Leduc, Charles A.
Glover, Hannah J.
De Rosa, Maria Caterina
Burnett, Lisa C.
Williams, Damian J.
Shang, Linshan
Goland, Robin
Tsang, Stephen H.
Wardlaw, Sharon
Egli, Dieter
Zheng, Deyou
Doege, Claudia A.
Leibel, Rudolph L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8262481
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8262481
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI146287
