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Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe s...

Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8266964

Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe signalling pathway

About this item

Full title

Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe signalling pathway

Publisher

New York: Springer US

Journal title

Journal of assisted reproduction and genetics, 2021-06, Vol.38 (6), p.1571-1588

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Purpose
Is it possible to eliminate metastasised chronic myeloid leukaemia (CML) and acute myeloid leukaemia (AML) cells from ovarian cortex fragments by inhibition of Aurora B/C kinases (AURKB/C) without compromising ovarian tissue or follicles?
Methods
Human ovarian cortex tissue with experimentally induced tumour foci of CML, AML and pr...

Alternative Titles

Full title

Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe signalling pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8266964

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8266964

Other Identifiers

ISSN

1058-0468

E-ISSN

1573-7330

DOI

10.1007/s10815-021-02081-9

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