Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from muri...
Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi
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Author / Creator
Duval, Cédric , Baranauskas, Adomas , Feller, Tímea , Ali, Majid , Cheah, Lih T. , Yuldasheva, Nadira Y. , Baker, Stephen R. , McPherson, Helen R. , Raslan, Zaher , Bailey, Marc A. , Cubbon, Richard M. , Connell, Simon D. , Ajjan, Ramzi A. , Philippou, Helen , Naseem, Khalid M. , Ridger, Victoria C. and Ariëns, Robert A. S.
Publisher
United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
The onset of venous thromboembolism, including pulmonary embolism, represents a significant health burden affecting more than 1 million people annually worldwide. Current treatment options are based on anticoagulation, which is suboptimal for preventing further embolic events. In order to develop better treatments for thromboembolism, we sought to...
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Full title
Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8271579
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8271579
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2103226118