Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial
Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial
About this item
Full title
Author / Creator
Fisher, Michael J. , Shih, Chie-Schin , Rhodes, Steven D. , Armstrong, Amy E. , Wolters, Pamela L. , Dombi, Eva , Zhang, Chi , Angus, Steven P. , Johnson, Gary L. , Packer, Roger J. , Allen, Jeffrey C. , Ullrich, Nicole J. , Goldman, Stewart , Gutmann, David H. , Plotkin, Scott R. , Rosser, Tena , Robertson, Kent A. , Widemann, Brigitte C. , Smith, Abbi E. , Bessler, Waylan K. , He, Yongzheng , Park, Su-Jung , Mund, Julie A. , Jiang, Li , Bijangi-Vishehsaraei, Khadijeh , Robinson, Coretta Thomas , Cutter, Gary R. , Korf, Bruce R. , Blakeley, Jaishri O. , Clapp, D. Wade and Neurofibromatosis Clinical Trials Consortium
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Neurofibromatosis type 1 (NF1) plexiform neurofibromas (PNs) are progressive, multicellular neoplasms that cause morbidity and may transform to sarcoma. Treatment of
Nf1
fl/fl
;
Postn
-Cre mice with cabozantinib, an inhibitor of multiple tyrosine kinases, caused a reduction in PN size and number and differential modulation of kinases...
Alternative Titles
Full title
Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial
Authors, Artists and Contributors
Author / Creator
Shih, Chie-Schin
Rhodes, Steven D.
Armstrong, Amy E.
Wolters, Pamela L.
Dombi, Eva
Zhang, Chi
Angus, Steven P.
Johnson, Gary L.
Packer, Roger J.
Allen, Jeffrey C.
Ullrich, Nicole J.
Goldman, Stewart
Gutmann, David H.
Plotkin, Scott R.
Rosser, Tena
Robertson, Kent A.
Widemann, Brigitte C.
Smith, Abbi E.
Bessler, Waylan K.
He, Yongzheng
Park, Su-Jung
Mund, Julie A.
Jiang, Li
Bijangi-Vishehsaraei, Khadijeh
Robinson, Coretta Thomas
Cutter, Gary R.
Korf, Bruce R.
Blakeley, Jaishri O.
Clapp, D. Wade
Neurofibromatosis Clinical Trials Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8275010
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8275010
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/s41591-020-01193-6
