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Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in...

Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8276267

Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma

About this item

Full title

Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer Immunology, Immunotherapy, 2021-03, Vol.70 (3), p.721-732

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Faithful tumor mouse models are fundamental research tools to advance the field of immuno-oncology (IO). This is particularly relevant in diseases with low incidence, as in the case of pediatric malignancies, that rely on pre-clinical therapeutic development. However, conventional syngeneic and genetically engineered mouse models fail to recapitula...

Alternative Titles

Full title

Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8276267

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8276267

Other Identifiers

ISSN

0340-7004

E-ISSN

1432-0851

DOI

10.1007/s00262-020-02713-6

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