Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas
Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas
About this item
Full title
Author / Creator
Friedman, Gregory K , Johnston, James M , Bag, Asim K , Bernstock, Joshua D , Li, Rong , Aban, Inmaculada , Kachurak, Kara , Nan, Li , Kang, Kyung-Don , Totsch, Stacie , Schlappi, Charles , Martin, Allison M , Pastakia, Devang , McNall-Knapp, Rene , Farouk Sait, Sameer , Khakoo, Yasmin , Karajannis, Matthias A , Woodling, Karina , Palmer, Joshua D , Osorio, Diana S , Leonard, Jeffrey , Abdelbaki, Mohamed S , Madan-Swain, Avi , Atkinson, T. Prescott , Whitley, Richard J , Fiveash, John B , Markert, James M and Gillespie, G. Yancey
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
A neurotropic herpes simplex virus that was genetically inactivated to prevent replication in normal cells was injected into the brain tumors of 12 patients with tumors that had progressed during previous treatment. Eleven patients had some radiographic or clinical responses, with inflammation detected in some PET scans. The median survival was 12....
Alternative Titles
Full title
Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas
Authors, Artists and Contributors
Author / Creator
Johnston, James M
Bag, Asim K
Bernstock, Joshua D
Li, Rong
Aban, Inmaculada
Kachurak, Kara
Nan, Li
Kang, Kyung-Don
Totsch, Stacie
Schlappi, Charles
Martin, Allison M
Pastakia, Devang
McNall-Knapp, Rene
Farouk Sait, Sameer
Khakoo, Yasmin
Karajannis, Matthias A
Woodling, Karina
Palmer, Joshua D
Osorio, Diana S
Leonard, Jeffrey
Abdelbaki, Mohamed S
Madan-Swain, Avi
Atkinson, T. Prescott
Whitley, Richard J
Fiveash, John B
Markert, James M
Gillespie, G. Yancey
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8284840
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8284840
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2024947
