MCP-1/CCR-2 axis in adipocytes and cancer cell respectively facilitates ovarian cancer peritoneal me...
MCP-1/CCR-2 axis in adipocytes and cancer cell respectively facilitates ovarian cancer peritoneal metastasis
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Author / Creator
Sun, Chaoyang , Li, Xi , Guo, Ensong , Li, Na , Zhou, Bo , Lu, Hao , Huang, Jia , Xia, Meng , Shan, Wanying , Wang, Beibei , Li, Kezhen , Weng, Danhui , Xu, Xiaoyan , Gao, Qinglei , Wang, Shixuan , Hu, Junbo , Lu, Yiling , Mills, Gordon B. and Chen, Gang
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Ovarian cancer selective metastasizes to the omentum contributing to the poor prognosis associated with ovarian cancer. However, the mechanism underlining this propensity and therapeutic approaches to counter this process has not been fully elucidated. Here, we show that MCP-1 produced by omental adipocytes binding to its cognate receptor CCR-2 on...
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Full title
MCP-1/CCR-2 axis in adipocytes and cancer cell respectively facilitates ovarian cancer peritoneal metastasis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8290627
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8290627
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-019-1090-1