C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute mye...
C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia
About this item
Full title
Author / Creator
Yusenko, Maria V. , Trentmann, Amke , Casolari, Debora A. , Abdel Ghani, Luca , Lenz, Mairin , Horn, Melanie , Dörner, Wolfgang , Klempnauer, Stefan , Mootz, Henning D. , Arteaga, Maria Francisca , Mikesch, Jan-Henrik , D’Andrea, Richard J. , Gonda, Thomas J. , Müller-Tidow, Carsten , Schmidt, Thomas J. and Klempnauer, Karl-Heinz
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Transcription factor MYB has recently emerged as a promising drug target for the treatment of acute myeloid leukemia (AML). Here, we have characterized a group of natural sesquiterpene lactones (STLs), previously shown to suppress MYB activity, for their potential to decrease AML cell proliferation. Unlike what was initially thought, these compound...
Alternative Titles
Full title
C/EBPβ is a MYB- and p300-cooperating pro-leukemogenic factor and promising drug target in acute myeloid leukemia
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8298201
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8298201
Other Identifiers
ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/s41388-021-01800-x
