Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer
Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer
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Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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Familial pancreatic cancer (FPC) is an established but rare inherited tumor syndrome that accounts for approximately 5% of pancreatic ductal adenocarcinoma (PDAC) cases. No major causative gene defect has yet been identified, but germline mutations in predisposition genes BRCA1/2, CDKN2A and PALB2 could be detected in 10–15% of analyzed families. T...
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Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8305658
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8305658
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ISSN
2075-4426
E-ISSN
2075-4426
DOI
10.3390/jpm11070631
